PhD Studentship: Single-cell arrays for stem cell heterogeneity and drug delivery studies

Posted by FM Earn On Monday, 16 February 2015 0 comments
University of Southampton - Bioengineering and Human factors, Faculty of Engineering and the Environment. Qualification type: PhD Location: Southampton Funding for: UK Students, EU Students Funding amount: The funding covers EU/UK fees and stipend in line with EPSRC rates Hours: Full Time Placed on: 11th February 2015 Expires: 11th May 2015 Reference: EngSci-BIO-127 Deadline: Applications will be accepted at any time until the position is filled. Microfluidic Single-Cell Arrays for Stem Cell Heterogeneity Studies In recent years an unexpected degree of variation in the response of genetically identical cells to biochemical signals has been discovered, which is highly relevant for stem cell research in general and regenerative medicine in particular. Traditional bulk assays do not give useful information because they present a read-out that is the average of many different cells. Heterogeneous cell populations should hence be studied at the single-cell level, preferably in a high-througput format that can address many individual cells simultaneously. This PhD project concerns the development of microfluidic cell arrays, where hundreds of cells are individually positioned by hydrodynamic forces, for the characterization of signalling heterogeneity in populations of mesenchymal stem cells. The project will seek to determine heterogeneity in the response to agents, delivered to the stem cells by nanoparticles, that can guide stem cell differentiation for regenerative medicine strategies. The PhD student will fabricate the cell traps with established soft lithography methods, will manipulate the cell samples and optimize their on-chip arraying, and will analyze the optical microscopy data with semi-automated image processing methods. We are thus looking for an engineer with a strong interest in biomedical applications or for a biochemist/biomedical scientist with an affinity for bioengineering approaches. You will work on the microfluidic cell arrays in a large interdisciplinary research group - Hybrid Biodevices (http://www.southampton.ac.uk/ifls/research/ifls/hybridbiodevices.page) - that operates at the interface between the Life Sciences and Electronic Engineering, and you will work on the stem cell cultures in the Centre for Human Development, Stem Cells and Regenerative Medicine (http://www.southampton.ac.uk/chdscr/), under the supervision of Dr Maurits de Planque (Electronics and Computer Science - http://www.ecs.soton.ac.uk/people/mdp) and Dr Nick Evans (Faculty of Medicine and Faculty of Engineering -http://www.southampton.ac.uk/medicine/about/staff/ndevans.page). Southampton's School of Electronics and Computer Science is one of the foremost Electronics and Electrical Engineering departments in the UK (see http://www.ecs.soton.ac.uk/about) with a strong commitment to research at the Life Sciences Interface through the Institute for Life Sciences (http://www.southampton.ac.uk/ifls/) , which also encapsulates the Bioengineering research of the Faculties of Medicine and Engineering. If you wish to discuss any details of the project informally, please contact Maurits de Planque, ECS, Email: mdp@ecs.soton.ac.uk Tel +44 (0)23 8059 9307 or Nick Evans, Bioengineering Sciences research group, Email: n.d.evans@soton.ac.uk, Tel: +44 (0) 23 8120 3293
READ MORE
University of Southampton Qualification type: PhD Location: Southampton Funding for: UK Students, EU Students Funding amount: The funding covers EU/UK fees and stipend in line with EPSRC rates Hours: Full Time Placed on: 11th February 2015 Expires: 11th May 2015 Reference: NGCM-32 Deadline: Applications will be accepted at any time until the position is filled. Recent government investment in driver-less car trials (http://www.trl.co.uk/news-hub/transport-news/latest-transport-news/?id=801764918) is accelerating us towards a future of greater automation in the transport network. As a direct result of this investment, the Transportation Research Laboratory (TRL) (http://www.trl.co.uk/) and the Transportation Research Group (TRG) at the University of Southampton are offering this research project investigating how transportation infrastructure can sustainably support high numbers of automated vehicles in the network. Existing transportation infrastructure is designed around non-automated vehicles. This includes not just the road-space but also the many thousands of traffic sensors, the control infrastructure (traffic lights, variable speed limits), the refuelling infrastructure and the integration between modes of transport (airports, train stations etc). This project will investigate strategies to redesign this infrastructure to support automated vehicles and deliver improvements in sustainability. The candidate in this project will have access to facilities and training to enable them to explore the scenario of high numbers of vehicles in the transportation network using techniques including: computational modelling, experiments using the TRL’s vehicle simulator and experiments using TRG’s instrumented vehicle. The candidate will be able to benefit from extended placements at the Transportation Research Laboratory as well as access to GATEway research partners for case studies (http://www.trl.co.uk/news-hub/trl-press-releases/2014/december/greenwichs-digital-credentials-driven-home-after-trl-led-consortium-wins-%C2%A38m-trial-to-pilot-futuristic-automated-vehicles/). The candidate will develop a broad understanding of both transportation infrastructure design/operation and vehicle automation. Ultimately the outcome of this research will be innovative new designs to transportation infrastructure – with a strong evidence base – that will support automated vehicles to maximize sustainability in the transport network. If you would like to discuss this project further please contact Dr Simon Box, Transportation Research Group Email: s.box@soton.ac.uk, Tel: +44 (0)2380 59 2175 Funding information: This project is in competition with others for the associated funding. The funding covers EU/UK fees and stipend. This project is run through participation in the EPSRC Centre for Doctoral Training in Next Generation Computational Modelling (http://ngcm.soton.ac.uk). For details of our 4 Year PhD programme, please see http://www.findaphd.com/search/PhDDetails.aspx?CAID=331&LID=2652.
READ MORE
University of Southampton - Structures and solid mechanics, Faculty of Engineering and the Environment Qualification type: PhD Location: Southampton Funding for: UK Students, EU Students Funding amount: The funding covers EU/UK fees and stipend in line with EPSRC rates Hours: Full Time Placed on: 11th February 2015 Expires: 11th May 2015 Reference: CMEES-FSI-123 Deadline: Applications will be accepted at any time until the position is filled. The use of lightweight composite materials has been rapidly increasing within aircraft. In military application the survivability of the aircraft is of utmost importance. This project aims to investigate the effect of fire on the structural integrity of carbon fibre reinforced plastic (CFRP) airframes. The project will combine experimental and numerical modelling of the structural performance of carbon fibre airframes subjected to fire and provide an assessment of their survivability in this harsh environment. This project is designed as an EngD programme, within which it is expected that at least 2 years of the research activities will take place at the Defence, Science and Technology Laboratories (DSTL) at Portsdown West. This position is only available to resident UK nationals and is subject to security clearance. If you wish to discuss any details of the project informally, please contact Dr Stephen Boyd, Fluid Structure Interaction research group, Email: s.w.boyd@soton.ac.uk, Tel: +44 (0) 2380 59 2375. The funding associated with this project covers EU/UK fees and stipend. Overseas students may have to cover the difference between EU/UK fees and international fees.
READ MORE
University of Southampton Qualification type: PhD Location: Southampton Funding for: UK Students, EU Students Funding amount: The funding covers EU/UK fees and stipend in line with EPSRC rates Hours: Full Time Placed on: 11th February 2015 Expires: 11th May 2015 Reference: NGCM-33 Deadline: Applications will be accepted at any time until the position is filled. Turbulent flows are ubiquitous in nature yet the practical models lack a firm theoretical basis. The field is currently being revolutionised by the application of large scale direct numerical simulations (DNS) in which no assumptions are made beyond those of a Newtonian fluid with Fourier heat conduction. However, such simulations are expensive and the high Reynolds number flows found in practice (such as in the atmosphere or on the wings of large aircraft) will remain beyond the capability of even the largest supercomputers for many decades to come. In this project, we will focus on a new class of algorithms based on a coupled multi-scale approach involving nested DNS. The methods are, in principle, capable of extension to high Reynolds numbers and parallelise very efficiently. We will test the methods on boundary-layer flows to demonstrate the capability and then take on the challenge of simulating high Reynolds number flow over an airfoil. If you wish to discuss any details of the project informally, please contact Neil Sandham, Aerodynamics and Flight Mechanics research group, Email: n.sandham@soton.ac.uk, Tel: +44 (0) 2380 59 4872. Funding information: This project is in competition with others for the associated funding. The funding covers EU/UK fees and stipend. This project is run through participation in the EPSRC Centre for Doctoral Training in Next Generation Computational Modelling (http://ngcm.soton.ac.uk). For details of our 4 Year PhD programme, please see http://www.findaphd.com/search/PhDDetails.aspx?CAID=331&LID=2652.
READ MORE

Professor of Energy Engineering

Posted by FM Earn On 0 comments
Become a part of one of the most exciting educational developments of our time. Nazarbayev University is a bold multi-billion dollar initiative to create a research university fit for the challenges of the 21st Century. Nazarbayev University is located in Astana, the new capital of Kazakhstan. The University operates a range of graduate and baccalaureate programs together with a Science and Innovation Park, 2 National Research Centers, 7 Hospitals and a Medical School. We work on a partnership model including 7 of the top-30 universities across the world to advance education, research and engagement with industry and society. We want to redefine people’s expectations of what contemporary higher education should be. We offer the chance to work in one of the most rapidly developing countries in the world. Astana is a family-friendly modern capital and the University is an outstandingly architected example of a campus environment. We offer an excellent pay and benefits package including generous home leave, high-quality accommodation and family-friendly policies for health-care and children’s education. Further information pertaining to the post can be found at: www.perrettlaver.com/microsite/nu/ Applications including a resume and a brief (no more than 4 pages) statement about how you would approach the role should uploaded to www.perrettlaver.com/microsite/nu/ by noon GMT on Friday 3rd April, quoting the relevant reference number above. Job Description As Professor at Nazarbayev University, the appointee will report to the Dean of the School and will be responsible for: Research conducting high quality research in their field of expertise and publish such research widely; applying for and attaining research grants and funding as appropriate for their field of research; attending relevant international conferences and developing broad networks; mentoring junior faculty and students to develop their research, grant applications and publications; assisting in the development of research Strategy in the relevant department and School. Teaching teaching undergraduate and postgraduate courses in their field of their expertise; engaging in course and program development when necessary; serving on and chairing Masters and PhD committees as needed; encouraging the development of innovative approaches to course design and delivery and ensuring that teaching design and delivery comply with the quality and educational standards and regulations of the department; challenging thinking, fostering debate and developing the students ability to engage in critical discourse and rational thinking. Academic Leadership performing informal management duties at the level of the Department, the School and the University; fostering the development of a vibrant and productive research culture in his or her field; serving on various committees at the School and University level. Internal / External Engagement developing and maintaining active networks, internally and externally, nationally and internationally; nurturing consultancy and research relationships with commerce, industry and in other external relationships including those with international collaborators, with professional and practitioner bodies, with policy communities, and with government agencies; actively contributing to developing academic, educational and research excellence in Kazakhstan. As Professor of Energy Engineering in the School of Engineering, the appointee will also be responsible for: leading and developing the PhD programme in Energy Engineering which launched in 2014; conducting leading research in the field of Energy Engineering which has relevance to and impact on the broader Kazakh energy industry, particularly petroleum engineering; playing an active role in the growth and development of the School regarding mentoring, leadership, morale and capacity building. Person specification Candidate for a Professorial position at Nazarbayev University much have the following experience, skills, qualification and attributes: Earned doctorate in a relevant field; An international reputation and visibility in his/her field of research; Publishing regularly in leading academic journals; Experience of mentoring junior faculty / a record of PhD supervision or equivalent; a collegiate approach and active contributor to the Schools development; strong communication and interpersonal skills; a strong reputation for delivering high quality taught programmes; Experience acquiring research funding from a variety of sources (including industry, national funding and University funding). As Professor of Energy Engineering in the School of School of Engineering, the appointee should also demonstrate: A world-leading publication record consistently in relevant top-tier journals; Experience, enthusiasm and vision for curriculum development at the PhD level; Extensive experience supervising PhDs to completion.
READ MORE

Professor of Biomedical Engineering

Posted by FM Earn On 0 comments
Become a part of one of the most exciting educational developments of our time. Nazarbayev University is a bold multi-billion dollar initiative to create a research university fit for the challenges of the 21st Century. Nazarbayev University is located in Astana, the new capital of Kazakhstan. The University operates a range of graduate and baccalaureate programs together with a Science and Innovation Park, 2 National Research Centers, 7 Hospitals and a Medical School. We work on a partnership model including 7 of the top-30 universities across the world to advance education, research and engagement with industry and society. We want to redefine people’s expectations of what contemporary higher education should be. We offer the chance to work in one of the most rapidly developing countries in the world. Astana is a family-friendly modern capital and the University is an outstandingly architected example of a campus environment. We offer an excellent pay and benefits package including generous home leave, high-quality accommodation and family-friendly policies for health-care and children’s education. Further information pertaining to the post can be found at: www.perrettlaver.com/microsite/nu/ Applications including a resume and a brief (no more than 4 pages) statement about how you would approach the role should uploaded to www.perrettlaver.com/microsite/nu/ by noon GMT on Friday 3rd April, quoting the relevant reference number above. Job Description As Professor at Nazarbayev University, the appointee will report to the Dean of the School and will be responsible for: Research conducting high quality research in their field of expertise and publish such research widely; applying for and attaining research grants and funding as appropriate for their field of research; attending relevant international conferences and developing broad networks; mentoring junior faculty and students to develop their research, grant applications and publications; assisting in the development of research Strategy in the relevant department and School. Teaching teaching undergraduate and postgraduate courses in their field of their expertise; engaging in course and program development when necessary; serving on and chairing masters and PhD committees as needed; encouraging the development of innovative approaches to course design and delivery and ensuring that teaching design and delivery comply with the quality and educational standards and regulations of the department; challenging thinking, fostering debate and developing the students ability to engage in critical discourse and rational thinking. Academic Leadership performing informal management duties at the level of the Department, the School and the University; fostering the development of a vibrant and productive research culture in his or her field; serving on various committees at the School and University level. Internal / External Engagement developing and maintaining active networks, internally and externally, nationally and internationally; nurturing consultancy and research relationships with commerce, industry and in other external relationships including those with international collaborators, with professional and practitioner bodies, with policy communities, and with government agencies; actively contributing to developing academic, educational and research excellence in Kazakhstan. As Professor of Biomedical Engineering in the School of Engineering, the appointee will also be responsible for: leading and developing the PhD programme in Biomedical Engineering which launched in 2014; conducting leading research in the field of Biomedical Engineering, particularly Biomedical Devices, which has relevance to and impact on the broader Kazakh healthcare industry; playing an active role in the growth and development of the School regarding mentoring, leadership, morale and capacity building. Person specification Candidate for a Professorial position at Nazarbayev University much have the following experience, skills, qualification and attributes: Earned doctorate in a relevant field; An international reputation and visibility in his/her field of research; Publishing regularly in leading academic journals; Experience of mentoring junior faculty / a record of PhD supervision or equivalent; a collegiate approach and active contributor to the Schools development; strong communication and interpersonal skills; a strong reputation for delivering high quality taught programmes; Experience acquiring research funding from a variety of sources (including industry, national funding and University funding). As Professor of Biomedical Engineering in the School of School of Engineering, the appointee should also demonstrate: A world-leading publication record consistently in relevant top-tier journals relating to Biomedical Engineering; Experience, enthusiasm and vision for curriculum development and teaching at the PhD level; Extensive experience supervising PhDs to completion.
READ MORE

Chair of the Department of Chemical Engineering

Posted by FM Earn On 0 comments
Become a part of one of the most exciting educational developments of our time. Nazarbayev University is a bold multi-billion dollar initiative to create a research university fit for the challenges of the 21st Century. Nazarbayev University is located in Astana, the new capital of Kazakhstan. The University operates a range of graduate and baccalaureate programs together with a Science and Innovation Park, 2 National Research Centers, 7 Hospitals and a Medical School. We work on a partnership model including 7 of the top-30 universities across the world to advance education, research and engagement with industry and society. We want to redefine people’s expectations of what contemporary higher education should be. We offer the chance to work in one of the most rapidly developing countries in the world. Astana is a family-friendly modern capital and the University is an outstandingly architected example of a campus environment. We offer an excellent pay and benefits package including generous home leave, high-quality accommodation and family-friendly policies for health-care and children’s education. Further information pertaining to the post can be found at: www.perrettlaver.com/microsite/nu/ Applications including a resume and a brief (no more than 4 pages) statement about how you would approach the role should uploaded to www.perrettlaver.com/microsite/nu/ by noon GMT on Friday 3rd April, quoting the relevant reference number above. Job Description As Chair of the Department of Chemical Engineering at Nazarbayev University, the appointee will report to the Dean of the School of Engineering and will be responsible for: Leadership providing academic leadership within the Department in all aspects of its operation to ensure that the mission, aims and objectives of the Department are met within the overall context of the School and University; managing the overall performance of the Department in line with the agreed strategy and key performance indicators; monitoring the progress of the Department against agreed objectives and targets identifying actions to encourage continuous development, with other colleagues as appropriate; leading, inspiring, developing and managing all staff reporting into the Chair. Research ensuring the conduct of the highest-quality research by all levels of academic faculty, to the required volume, in accordance with the research strategy; ensuring the delivery of a high standard of research supervision; leading and pursuing his/her own programme of research as appropriate. Internal / External Engagement leading the Department to develop and maintain active networks, internally and externally, nationally and internationally; leading the Department’s endeavours in consultancy, in contract research relationships with commerce and industry, and in other external relationships including those with international collaborators, with professional and practitioner bodies, with policy communities, and with government agencies. Teaching & Programme Development/Management working closely with the Director of Studies in development and delivery of a robust and effective Department teaching and learning strategy that supports the School and University strategy and in programme and curriculum development as best serves the goals of the School and the Department; contributing to the taught programmes of the Department as appropriate; ensuring efficient management and operation of undergraduate and postgraduate programmes, including programme design and development, compliance with review and validation procedures, overall management of delivery, assessment and student recruitment and admission. Departmental Management delivering efficient and effective financial management and use of resources; overseeing the recruitment of faculty staff as the Department grows to steady state; representing the Department on senior University committees and externally, as appropriate. The Chair of Department may be asked to carry out such other duties and responsibilities the Provost or Dean of the School may from time-to-time prescribe. As Chair of the Department of Chemical Engineering, the appointee will also be responsible for: overseeing the work of the undergraduate, Masters and PhD programme directors; building capacity across all programmes and overseeing the significant growth of the department; developing and recruiting new faculty members in line with growth; implementing change sensitively and diplomatically when required. Person specification Candidates for the role of the Chair of Department at Nazarbayev University much have the following experience, skills, qualification and attributes: Earned doctorate; demonstrable leadership and an international reputation in his/her field of research; strong strategic skills; a collegiate approach with the ability to foster the strategic ambitions of others; financial acumen and proven managerial ability; strong communication and interpersonal skills; significant experience of academic and administrative leadership and management at senior level; relevant experience of and commitment to programme and curriculum development along with a strong personal record of delivering taught programmes; demonstrable ability to motivate and build morale and team spirit; ability to promote the aims of the Department to the academic community within and across the School and Nazarbayev University, and externally to international funding bodies and relevant organisation; capacity to work in partnership on research and development issues. As Chair of the Department of Chemical Engineering, the appointee should also demonstrate: experience as a full professor or equivalent at a leading institution; a flexible and dynamic leadership style which can easily adapt to change; Previous experience in a formal managerial role. Research accomplishment in Petrochemical Engineering to relate closely to the petrochemical industry in Kazakhstan;
READ MORE